Real time, small animal whole body imaging platform for fast screening of all PET radiopharmaceuticals
Features
- Small animal, PET isotope, live imaging platform
- Real time, whole body imaging post injection
- Fast screening of radiolabeled compounds
- Suitable for Radio-TLC and organ ex vivo imaging
- Compatible with 3rd party anesthesia and vital signs monitoring systems
Performance
- Weight less than 40kg
- Dimensions: 43cm (L) x 46cm (W) x 43cm (H)
- <1.2mm spatial resolution at Center of Field of View
- Sensitivity of 2.9% at Center of Field of View
- Time-of-Flight performance for improved Signal-to-Noise ratio
- Down to 10 seconds frames for whole body scans
- Energy resolution of 12.4% at 511 keV
Definition of a user friendly platform
- Straightforward workflow with easy imaging protocol set-up
- Easy to operate by non highly-experienced professionals
- Footprint allowing for easy system installation and transfer
- Ideal for imaging inside a clean room, or next to a cyclotron
- Visual | eyesTM software hub for post processing of imaging data
Applications
[18]F imaging using β-eye™
Free F-18 accumulating in bones. Image acquired at BIOEMTECH preclinical laboratories. Image info: 1h post injection acquisition, 10 min static scan. Total injected dose: 70 uCi / 2.59 MBq
Applications
[18]F-FDG imaging with wild-type zebra fish, using β-eye™
In this very exciting case, wild-type, adult zebrafish were injected intravenously or intraperitoneally with several 18F-FDG activities and imaged on β-eye™ benchtop PET tracer imaging system. Acquisitions were conducted right after injection, with a 6-8 minutes study duration. Brain, heart, swimming bladder, and point of injection were easily distinguishable in acquisitions of animals injected intravenously. Here, we present an example of an adult zebrafish injected intravenously with 0.16 MBq / 4.25 uCi and imaged right after injection. The study duration was equal to 6 minutes. This work was conducted in collaboration with Dr. Vasiliki Tsata , from the Biomedical Research Foundation of the Academy of Athens.
Publications
- A fluorophore-conjugated reagent enabling rapid detection, isolation and live tracking of senescent cellsRead More
- A technique to quantify very low activities in regions of interest with a collimatorless detectorRead More
- Preparation, Radiolabeling with 68Ga/177Lu and Preclinical Evaluation of Novel Angiotensin Peptide Analog: A New Class of Peptides for Breast Cancer TargetingRead More
- Preclinical Evaluation of a Lead Specific Chelator (PSC) Conjugated to Radiopeptides for 203Pb and 212Pb-Based TheranosticsRead More
- Practical considerations for navigating the regulatory landscape of non‑clinical studies for clinical translation of radiopharmaceuticalsRead More
- β-eye™: A benchtop system for in vivo molecular screening of labeled compoundsRead More
- Evaluation of Hamamatsu H13974 Large Sensitive Area Flat Panel PMT Array for Use in Small Animal Imaging and ScintimammographyRead More
- Characterization of “γ-eye™”: a Low-Cost Benchtop Mouse-Sized Gamma Camera for Dynamic and Static Imaging StudiesRead More
- 212Pb-DOTAM-peptide targeting LDLR-receptors in glioblastoma and pancreatic ductal adenocarcinomaRead More
Looking for more info on the β-eye™ and its applications?
Download the β-eye™ Brochure