A desktop preclinical 3D SPECT platform for fast in vivo screening and longitudinal imaging of gamma- and alpha-emitting radiopharmaceuticals

From fast planar imaging to dynamic 3D SPECT

The γ-eye™ system now supports tomographic 3D SPECT imaging, enabling enhanced spatial assessment while preserving its compact footprint and simplicity

  • 3D SPECT imaging for spatial assessment of radiopharmaceutical distribution and longitudinal evaluation across different time points
  • 4D dynamic SPECT imaging, enabling quantitative kinetic analysis of radiotracer uptake
  • Fast planar imaging for simple and time-efficient screening, such as the assessment of whole-body distribution and compound kinetics
  • High-throughput imaging of up to four mice simultaneously or one rat*

 

*Available only for planar imaging

High Throughput configuration

High-throughput imaging for multi-animal screening

The γ-eye™ is also available in a High Throughput configuration, designed for efficient planar imaging of larger study cohorts while preserving the core functionality of the standard system

  • Field of view of 100 × 200 mm, providing extended coverage for multi-animal imaging
  • Planar imaging of up to 4 mice simultaneously or 1 rat, supporting efficient screening workflows
  • High-throughput performance of more than 110 mouse scans per day, increasing daily imaging capacity for larger study cohorts

Designed for the demands of advanced radiopharmaceutical research

  • Optimised for alpha-emitting radiopharmaceuticals, supporting demanding preclinical imaging workflows across a broad range of radionuclides
  • Whole-body dynamic imaging from the moment of administration, enabling early assessment of distribution and kinetics
  • Energy-resolved imaging across complex decay chains, for studying daughter redistribution and spatial separation
  • User-friendly workflow and desktop design with user-interchangeable collimators

Technical performance in a desktop format

  • State-of-the-art detector architecture and components
  • < 1.6 mm spatial resolution
  • Down to 1 sec frames for whole-body planar imaging and 5 min frames for whole-body 3D SPECT imaging
  • Energy resolution down to 11%
  • Detectable energy range of 35-440 keV
  • Available with 2 user-interchangeable collimators for different imaging requirements
  • Compatible with 3rd party anesthesia and Vital Signs monitoring system
    Ac-225 all peaks

    Applications

    Oncology, alpha emitters

    Longitudinal multi-window 3D SPECT imaging of ²²⁵Ac-Trastuzumab

    Combining multiple energy windows to assess radiopharmaceutical distribution under reduced-count conditions

    Image info: 48 h post injection - 30 min scan duration - 172kBq injected activity
    Study performed in BIOEMTECH Laboratories and presented at TERACHEM 2026

    Applications

    Oncology, beta emitters

    Dynamic 4D SPECT imaging of ¹⁷⁷Lu-Trastuzumab

    Early whole-body distribution and 3D SPECT imaging across higher- and lower-activity conditions

    Image info: 3-53 min post injection - 5 min frame duration – 40.2 MBq activity during imaging

    Study performed in BIOEMTECH Laboratories

    Applications

    Planar imaging

    Extending SPECT workflows with fast planar imaging

    Fast whole-body planar imaging for rapid assessment of radiopharmaceutical distribution and early kinetics across a broad range of radionuclides

    Image info: 0-60 min post injection - down to 10 sec frames - 30 MBq injected activity
    Study performed in collaboration with the Radiopharmaceutical Chemistry Group at INRASTES, NCSR "Demokritos" (Dr. Ioannis Pirmetttis) and NuclearPharm

    Ag111 phantom study

    Applications

    Theranostics

    Evaluation of preclinical quantitative imaging of ¹¹¹Ag

    Optimization and validation in a mouse phantom

    Ac225 phantom

    Applications

    Quantification phantom studies across multiple radionuclides

    Mouse phantom studies demonstrating the ability of γ-eye™ to image and quantify a broad range of diagnostic and therapeutic radionuclides across isotope-specific energy windows.

    Studies performed in BIOEMTECH Laboratories

    γ-eye front page

    γ-eye™ Performance Highlights

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