A desktop preclinical 3D SPECT platform for fast in vivo screening and longitudinal imaging of gamma- and alpha-emitting radiopharmaceuticals
From fast planar imaging to dynamic 3D SPECT
The γ-eye™ system now supports tomographic 3D SPECT imaging, enabling enhanced spatial assessment while preserving its compact footprint and simplicity
- 3D SPECT imaging for spatial assessment of radiopharmaceutical distribution and longitudinal evaluation across different time points
- 4D dynamic SPECT imaging, enabling quantitative kinetic analysis of radiotracer uptake
- Fast planar imaging for simple and time-efficient screening, such as the assessment of whole-body distribution and compound kinetics
- High-throughput imaging of up to four mice simultaneously or one rat*
*Available only for planar imaging
High-throughput imaging for multi-animal screening
The γ-eye™ is also available in a High Throughput configuration, designed for efficient planar imaging of larger study cohorts while preserving the core functionality of the standard system
- Field of view of 100 × 200 mm, providing extended coverage for multi-animal imaging
- Planar imaging of up to 4 mice simultaneously or 1 rat, supporting efficient screening workflows
- High-throughput performance of more than 110 mouse scans per day, increasing daily imaging capacity for larger study cohorts
Designed for the demands of advanced radiopharmaceutical research
- Optimised for alpha-emitting radiopharmaceuticals, supporting demanding preclinical imaging workflows across a broad range of radionuclides
- Whole-body dynamic imaging from the moment of administration, enabling early assessment of distribution and kinetics
- Energy-resolved imaging across complex decay chains, for studying daughter redistribution and spatial separation
- User-friendly workflow and desktop design with user-interchangeable collimators
Technical performance in a desktop format
- State-of-the-art detector architecture and components
- < 1.6 mm spatial resolution
- Down to 1 sec frames for whole-body planar imaging and 5 min frames for whole-body 3D SPECT imaging
- Energy resolution down to 11%
- Detectable energy range of 35-440 keV
- Available with 3 user-interchangeable collimators for different imaging requirements
- Compatible with 3rd party anesthesia and Vital Signs monitoring system
Applications
Oncology, alpha emitters
3D SPECT imaging across the ²²⁵Ac decay chain
Multi-window imaging of ²²⁵Ac-Trastuzumab in a SKOV3 tumor model
Image info: 48 h post injection - 30 min scan duration - 172kBq injected activity
Study performed in BIOEMTECH Laboratories
Applications
Theranostics
Evaluation of preclinical quantitative imaging of ¹¹¹Ag
Optimization and validation in a mouse phantom
Applications
Oncology, alpha-emitters
Preclinical imaging of theranostics
²²⁵Ac-labelled FAPI-targeting agent on a HEK-FAP mouse model
Images info: 24h post injection – 20min scan – injected activity 0.19MBq
Applications
Oncology
Preclinical imaging of a theranostic pair
Tumor imaging with ²⁰³Pb - ²¹²Pb (PSC-PEG-T compound)
Images info: 24h post injection – 10min scan with 30sec frames - injected activity 0.89MBq & 0.02MBq accordingly
Applications
Bone imaging
Imaging the path of theranostics
Free ¹⁷⁷Lu accumulation in the bones of a healthy mouse
Image info: 24h post injection - 20min scan - injected activity 20MBq
Applications
Oncology
Preclinical imaging of diagnostic agents
Assessing the efficacy of ¹¹¹In-DOTATATE in targeting tumors, with and without the use of tumor protection.
Images info: 3h post injection - 6min scan - injected activity 4MBq
Applications
Visualizing diagnostic pathways
Accumulation of ⁹⁹ᵐTc-MIBI radiopharmaceutical
Image info: 24h post injection – 10min scan – injected activity 3MBq
