Preclinical research is the more systematic method of studying new drugs (diagnostic and therapeutic), molecular mechanisms, other biomolecules and recently nanoparticles. Over the past 15 years, preclinical research uses molecular imaging as a basic tool, utilizing the interaction of various forms of radiation with tissues and extracting functional and / or anatomical information on the in-vivo biodistribution of radiopharmaceuticals.
The aim of NAVIGATE project is:
- Development and optimization of a new series of preclinical imaging systems for the in-vivo characterization of new drugs and biomolecules
- Development of new methodologies and protocols for accurate, fast and cost-effective evaluation of different drugs and biomolecules
The main features of the new imaging systems are:
- Low cost, making them accessible to all research teams,
- Small dimensions that make them really portable and
- Ease of use, without requiring specialized personnel and installation areas
The above-mentioned features make this new series of imaging systems innovative and differentiate it from the currently available commercial systems.
BIOEMTECH’s team are young scientists with 10 years’ experience in the development of prototype systems and participation of European projects for the study of new biomolecules and pharmaceuticals. BIOEMTECH developed an in-vivo imaging platform for small animals to understand molecular mechanisms and to monitor in real-time the biodistribution of new drugs / substances in the body.
Our vision is to change the way preclinical pharmaceutical research is carried out, to accelerate it and to offer innovative, everyday tools for all groups developing new drugs or biomolecules using animal models. These methods are in line with bioethics rules for minimizing the number of animals used.
NAVIGATE project and more specifically the improvement and development of new, portable, economic, preclinical imaging systems, it is expected that pharmaceutical research will be assisted through optimized methodologies and protocols, new standards and services will be created, research teams will be more competitive, education will be strengthened and eventually will benefit the health system.