Breast cancer: 4T1 Syngeneic Mouse Model

Breast cancer is one of the leading causes of death in women across the globe. Although significant advances in research, diagnosis and treatment of the disease have been made in the last decades, it still remains a major health concern. In 2022 approximately 2.3 million women diagnosed with breast cancer globally and 670,000 of them died. Although age is a predisposing factor, young women are not “immune” to the disease. Women under the age of 40 account for the 5-7% of all breast cancers making it the highest diagnosed cancer for this age group. The modest improvements in treating the disease by established therapeutic methods have led both the scientific community and pharmaceutical industry in a quest of new approaches. Animal models are an invaluable tool for testing the efficacy and safety of these novel approaches.