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1. Have a full biodistribution data set, for all time points post injection, non-invasively, using only one animal.

  • Ηaving the same animal for all time-points, significantly improves statistics and accuracy of studies, while minimizing the number of required animals per study.
  • Efficient animal use significantly reduces cost, as well as time required to understand how a new product behaves, thus enabling the testing of different product variations.
  • The “eyes” can be used as a quality assurance tool of the biodistribution test sample, identifying bad injections or animals with “unexpected” behavior before proceeding to the ex-vivo study.
  • By using fewer animals, groups performing biodistributions can easily comply with bio-ethical standards and the 3Rs Principle by significantly reducing number of animals used.

2. Obtain whole body images easily, right from the first second post injection.

3. Speed up ex-vivo biodistributions by imaging all organs in a single view.

4. Provide semi-quantitative planar images of significantly higher resolution, with no penetration depth limit at a much lower cost compared to optical imaging.

5. Optimize your imaging protocols by:

  • defining  the optimal time points to image;
  • studying the effect of different preparation conditions;
  • testing alternative administration routes;
  • optimizing injected concentrations;
  • dynamic imaging of the first minutes post injection.

6. Fully exploit an advanced multimodal imaging system by only scanning at the optimal times, tracers, conditions, animals:

  • By first defining all the optimal parameters through the “eyes”, you can significantly reduce the cost, time and accuracy of conducted studies and ensure that no tomographic 3D scans goes discarded.

Download our eyes’ applications brochure here.

For more detailed information on the various uses of the eyes-series, click here.