Real-time, in vivo rodent imaging, allows researchers to observe and monitor several normal and abnormal biological processes. Data collected using the eyes series, provides crucial initial insights and generate quantitative results that, in combination with the Visual | eyes interface, compose an essential platform for every preclinical laboratory.
Oncology
Non-invasively assess your agent's targeting properties, real-time monitor drug delivery and track tumor progression.
Infection, Inflammation
Acquire detailed insights into disease mechanisms, enhance more accurate diagnostics while supporting the development or improvement of new or already existing therapeutics.
Protocol optimization
Test different animal preparation conditions, drug concentrations and administration routes to optimize your protocols.
Quick insights
Scan the same mouse at multiple time points to determine the optimal moments for 3D imaging. Conduct super-fast QC to exclude faulty injected subjects from further and more complex studies.
Applications with eyes™
[18]F-FDG imaging with wild-type zebra fish, using β-eye™
In this very exciting case, wild-type, adult zebrafish were injected intravenously or intraperitoneally with several 18F-FDG activities and imaged on β-eye™ benchtop PET tracer imaging system. Acquisitions were conducted right after injection, with a 6-8 minutes study duration. Brain, heart, swimming bladder, and point of injection were easily distinguishable in acquisitions of animals injected intravenously. Here, we present an example of an adult zebrafish injected intravenously with 0.16 MBq / 4.25 uCi and imaged right after injection. The study duration was equal to 6 minutes. This work was conducted in collaboration with Dr. Vasiliki Tsata , from the Biomedical Research Foundation of the Academy of Athens.
[18]F imaging using β-eye™
Free F-18 accumulating in bones. Image acquired at BIOEMTECH preclinical laboratories. Image info: 1h post injection acquisition, 10 min static scan. Total injected dose: 70 uCi / 2.59 MBq
Oncology, Alpha Emitters
[225]Ac imaging using γ-eye™
In vivo imaging of alpha-emitting isotopes made possible, with BIOEMTECH technology. Two illustrative images, from two timepoints: 2h and 24h post injection with a Ac-225 radiopharmaceutical, in an oncology model. Scan duration 10 min. Dose injected: 3.5 uCi / 0.13 Mbq. Images acquired at Radiomedix laboratories.