Real-time, in vivo rodent imaging, allows researchers to observe and monitor several normal and abnormal biological processes. Data collected using the eyes series, provides crucial initial insights and generate quantitative results that, in combination with the Visual | eyes interface, compose an essential platform for every preclinical laboratory.
Oncology
Non-invasively assess your agent's targeting properties, real-time monitor drug delivery and track tumor progression.
Infection, Inflammation
Acquire detailed insights into disease mechanisms, enhance more accurate diagnostics while supporting the development or improvement of new or already existing therapeutics.
Protocol optimization
Test different animal preparation conditions, drug concentrations and administration routes to optimize your protocols.
Quick insights
Scan the same mouse at multiple time points to determine the optimal moments for 3D imaging. Conduct super-fast QC to exclude faulty injected subjects from further and more complex studies.
Applications with eyes™
Oncology, BLI
Tumor imaging with a bioluminescent dye
Use of D-Lusiferin as a bioluminescence reporter in a non-orthotopic glioblastoma tumor. Image info: Injected concentration 3mg - Injected volume 200μL - Acquisition time 30min
Oncology, FLI
Studying Epidermoid Carcinoma
Case study of in vivo therapy evaluation and staging of Epidermoid Carcinoma (also named Squamous cell carcinoma) in preclinical models using Fluorescence Optical Imaging. RFP dyes used.
Oncology, FLI
Tumor imaging using the φ-eye™
tdTomato is a basal (constitutively fluorescent) orange fluorescent protein with excitation wavelength~554nm and emission wavelength~581nm, that can be used for tumor imaging. Here is an example in a neurofibroma model, using tdTomato dye intravenously administrated.