Real-time, in vivo rodent imaging, allows researchers to observe and monitor several normal and abnormal biological processes. Data collected using the eyes series, provides crucial initial insights and generate quantitative results that, in combination with the Visual | eyesTM interface, compose an essential platform for every preclinical laboratory.
Oncology
Non-invasively assess your agent's targeting properties, real-time monitor drug delivery and track tumor progression.
Infection, Inflammation
Acquire detailed insights into disease mechanisms, enhance more accurate diagnostics while supporting the development or improvement of new or already existing therapeutics.
Protocol optimization
Test different animal preparation conditions, drug concentrations and administration routes to optimize your protocols.
Quick insights
Scan the same mouse at multiple time points to determine the optimal moments for 3D imaging. Conduct super-fast QC to exclude faulty injected subjects from further and more complex studies.
Applications with eyes™
PET
Using Zr-89 for lungs imaging
In vivo imaging of free Zr-89 accumulation in the lungs of a healthy mouse following intratracheal administration. Imaging parameters: 30 min post-administration static acquisition - injected activity 94.4 μCi - acquisition time 5min.
Oncology, PET
Cardiac PET imaging using F-18 FDG
2D imaging allows us to detect critical features, such as a tumor in necrosis. However, the incorporation of 3D capabilities enables a further advancement in the resolution of structures and functions within vital organs, such as the heart, thereby facilitating a more comprehensive understanding. Image info: 1 hr post injection acquisition - 60 min dynamic scan - total injected dose 5.45MBq
PET
F-18 FDG imaging with wild-type zebra fish, using β-eye™
Here, we present an example of an adult zebrafish injected intravenously with F-18 FDG on a dose of 0.16 MBq / 4.25 μCi and imaged right after injection. The study duration was equal to 6 minutes. Several organs were easily distinguishable. This work was conducted in collaboration with Dr. Vasiliki Tsata , from the Biomedical Research Foundation of the Academy of Athens.