Real-time, in vivo rodent imaging, allows researchers to observe and monitor several normal and abnormal biological processes. Data collected using the eyes series, provides crucial initial insights and generate quantitative results that, in combination with the Visual | eyes interface, compose an essential platform for every preclinical laboratory.
Oncology
Non-invasively assess your agent's targeting properties, real-time monitor drug delivery and track tumor progression.
Infection, Inflammation
Acquire detailed insights into disease mechanisms, enhance more accurate diagnostics while supporting the development or improvement of new or already existing therapeutics.
Protocol optimization
Test different animal preparation conditions, drug concentrations and administration routes to optimize your protocols.
Quick insights
Scan the same mouse at multiple time points to determine the optimal moments for 3D imaging. Conduct super-fast QC to exclude faulty injected subjects from further and more complex studies.
Applications with eyes™
SWIR, FLI
Imaging healthy mice in the SWIR window
BIOEMTECH's technology enables imaging in the Short Wavelength InfraRed (SWIR) window. This example demonstrates clear visualization of the saphenous vein in a healthy mouse. Imaging parameters: Indocyanine Green (ICG) dye, injected volume 100 μL, concentration 500 μM, 1 min post-injection (p.i.) and 5 ms exposure time.
Inflammation, FLI
Bone imaging using the φ-eye™
In vivo fluorescence imaging of bone was performed using a probe with an emission wavelength of 680 nm in a mouse model of spondyloarthritis. This approach offers a powerful tool for monitoring disease progression and evaluating the efficacy of novel therapeutic interventions.
Oncology, 3D
Cardiac PET imaging using [18]F-FDG
2D imaging allows us to detect critical features, such as a tumor in necrosis. However, the incorporation of 3D capabilities enables a further advancement in the resolution of structures and functions within vital organs, such as the heart, thereby facilitating a more comprehensive understanding. Image info: 1 hr post injection acquisition - 60 min dynamic scan - total injected dose 5,45MBq