Real-time, in vivo rodent imaging, allows researchers to observe and monitor several normal and abnormal biological processes. Data collected using the eyes series, provides crucial initial insights and generate quantitative results that, in combination with the Visual | eyes interface, compose an essential platform for every preclinical laboratory.
Oncology
Non-invasively assess your agent's targeting properties, real-time monitor drug delivery and track tumor progression.
Infection, Inflammation
Acquire detailed insights into disease mechanisms, enhance more accurate diagnostics while supporting the development or improvement of new or already existing therapeutics.
Protocol optimization
Test different animal preparation conditions, drug concentrations and administration routes to optimize your protocols.
Quick insights
Scan the same mouse at multiple time points to determine the optimal moments for 3D imaging. Conduct super-fast QC to exclude faulty injected subjects from further and more complex studies.
Applications with eyes™
Oncology
[111]In-Dotatate imaging using the γ-eye™
The objective of this study was to assess the efficacy of 111In-Dotatate in targeting tumors, with and without the additional use of tumor protection. The images were acquired 3 hours post-injection, with a 6 min static scan. The total injected dose was 108 µCi /3.99 MBq.
[99m]Tc imaging using the γ-eye™
Study conducted on a healthy mouse that was injected intravenously with 500μCi (first image from the left) and 300μCi (two subsequent images). We can observe the kinetics of the compound into the body of the mouse, as well as its accumulation at the liver and kidney.
[18]F-FDG imaging with wild-type zebra fish, using β-eye™
Here, we present an example of an adult zebrafish injected intravenously with 18F-FDG on a dose of 0.16 MBq / 4.25 uCi and imaged right after injection. The study duration was equal to 6 minutes. Several organs were easily distinguishable. This work was conducted in collaboration with Dr. Vasiliki Tsata , from the Biomedical Research Foundation of the Academy of Athens.