Real-time, in vivo rodent imaging, allows researchers to observe and monitor several normal and abnormal biological processes. Data collected using the eyes series, provides crucial initial insights and generate quantitative results that, in combination with the Visual | eyesTM  interface, compose an essential platform for every preclinical laboratory.

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Oncology

Non-invasively assess your agent's targeting properties, real-time monitor drug delivery and track tumor progression.

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Infection, Inflammation

Acquire detailed insights into disease mechanisms, enhance more accurate diagnostics while supporting the development or improvement of new or already existing therapeutics.

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Protocol optimization

Test different animal preparation conditions, drug concentrations and administration routes to optimize your protocols.

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Quick insights

Scan the same mouse at multiple time points to determine the optimal moments for 3D imaging. Conduct super-fast QC to exclude faulty injected subjects from further and more complex studies.

Applications with eyes™

Oncology, FLI

Tumor imaging using the φ-eye™

tdTomato, a constitutively fluorescent orange protein (excitation ~554 nm, emission ~581 nm), is utilized for tumor imaging applications. This example demonstrates its use in a neurofibroma model, with the dye administered intravenously to enable fluorescence-guided imaging.

SWIR, FLI

Imaging healthy mice in the SWIR window

BIOEMTECH's technology enables imaging in the Short Wavelength InfraRed (SWIR) window. This example demonstrates clear visualization of the saphenous vein in a healthy mouse. Imaging parameters: Indocyanine Green (ICG) dye, injected volume 100 μL, concentration 500 μM, 1 min post-injection (p.i.) and 5 ms exposure time.

Inflammation, FLI

Bone imaging using the φ-eye™

In vivo fluorescence imaging of bone was performed using a probe with an emission wavelength of 680 nm in a mouse model of spondyloarthritis. This approach offers a powerful tool for monitoring disease progression and evaluating the efficacy of novel therapeutic interventions.