Real-time, in vivo rodent imaging, allows researchers to observe and monitor several normal and abnormal biological processes. Data collected using the eyes series, provides crucial initial insights and generate quantitative results that, in combination with the Visual | eyesTM interface, compose an essential platform for every preclinical laboratory.
Oncology
Non-invasively assess your agent's targeting properties, real-time monitor drug delivery and track tumor progression.
Infection, Inflammation
Acquire detailed insights into disease mechanisms, enhance more accurate diagnostics while supporting the development or improvement of new or already existing therapeutics.
Protocol optimization
Test different animal preparation conditions, drug concentrations and administration routes to optimize your protocols.
Quick insights
Scan the same mouse at multiple time points to determine the optimal moments for 3D imaging. Conduct super-fast QC to exclude faulty injected subjects from further and more complex studies.
Applications with eyes™
Oncology, BLI
Tumor imaging using a bioluminescent substrate
This study demonstrates the use of D-Luciferin as a substrate for bioluminescence imaging in a non-orthotopic glioblastoma tumor model. Imaging was performed at day 3 and 10 after the inoculation of 1 million U87MG-Luc2 cells. Key parameters: injected concentration of 3 mg, injection volume of 200 μL saline and exposure time of 5 minutes.
PET
Using F-18 for bone imaging
Free F-18 accumulating in bones. Image acquired at BIOEMTECH preclinical laboratories. Image info: 1h post injection acquisition, 10 min static scan. Total injected dose: 70 uCi / 2.59 MBq